A set of tubes containing different COVID-19 variants

COVID-19 Variants: The 4 Most Important Things You Need To Know


With COVID-19 vaccines becoming more widespread, so do questions and concerns regarding new COVID-19 variants. Here are four of the most important things you need to keep track of when it comes to COVID-19 variants:

  • COVID-19 variants were always expected to develop.
  • The vaccine can protect you from the most common variants in the U.S.  
  • Constant testing helps identify new variants.
  • Classifications of variants help gauge their impact on health.
     

Read more about each item below.

COVID-19 Variants Are Inevitable

Viruses usually change through mutation, so seeing new variants over time is always expected. New virus variants will appear and disappear, though some will persist. The COVID-19 cases recorded since last year result from a variant from the U.K., with hundreds more unique to each state.

The Different COVID-19 Variants

There are already multiple highly infectious variants of the virus circulating worldwide and in the United States, all of which have links to high transmission rates. Although these variants may sound concerning because of the higher numbers of cases linked to them, getting vaccinated should provide adequate protection. Here are the SARS-CoV-2 variants that are currently present in the United States:

1. U.K. Variant (B.1.1.7)

Initially detected in the United Kingdom, this variant of the SARS-CoV-2 virus was first identified in the U.S. in December 2020. Vaccines have proved to be highly effective against this variant of the virus, which CDC Director Rochelle Walensky has noted as the dominant strain in the U.S.

2. South Africa Variant (B.1.351)

This variant was initially detected in South Africa in December 2020. It is also reported to have high transmissibility rates due to the multiple mutations on its spike protein.

3. Brazil Variant (P.1)

First discovered in travelers from Brazil during a screening at an airport in Japan back in January 2021, it is now widely circulating in places as far away as South Korea and the Faroe Islands. 

4. California Variant (B.1.427 and B.1.429)

This variant was identified in California as early as January 2021. It is associated with the outbreaks in California, and it has viral mutations located on the spike protein of the virus. 

5. Texas Variant (BV-1)

This recent variant was discovered in the Brazos Valley in Texas during an ongoing testing program. It is closely related to the U.K. variant that is the dominant strain in the U.S. It has similar genetic markers associated with rapid spread and severe symptoms, although the student from whom the sample was taken presented with only mild symptoms.

How COVID-19 Variants Are Identified

Scientists identify COVID-19 variants using a process called genomic sequencing. This involves decoding genes to learn more about the virus itself. This lets scientists monitor how the virus changes, how these changes affect its characteristics, and how these new characteristics may impact our health. The CDC employs various tactics in tracking variants of COVID-19, such as coordinating with state health departments, public health agencies, commercial diagnostic laboratories, and universities to test and sequence thousands of samples from across the country.

How COVID-19 Variants Are Classified

The United States Department of Health and Human Services (HHS) developed a system for characterizing and classifying variants of SARS-CoV-2. 

1. Variant of Interest

These variants come with genetic markers that are thought to affect transmissions, have caused unique outbreak clusters, or have limited prevalence within an area. Examples of these strains are the ones that are unique to New York.

2. Variant of Concern

These viral mutations have evidence of higher transmissibility and increased severity of the disease. The variants from the U.K., Brazil, South Africa, and California are grouped under this classification.

3. Variant of High Consequence

This variant of the virus is highly resistant to antibodies following a previous infection or vaccination, is resistant to Emergency Use Authorization (EUA) therapy, causes severe clinical disease, and increases hospitalizations. There are currently no COVID-19 variants under this classifiction.

Viral mutations occur the more they are transmitted, so it’s crucial to get tested once you suspect symptoms. Not only will this provide helpful information on current circulating COVID-19 variants, but it will also help get you the best care and treatment. Learn more about St. Joseph Health’s testing capabilities at our Respiratory Care Clinic in College Station.

Sources:

CNN | CDC Director: UK Variant is Now Dominant COVID-19 Strain in the US

CNN | New Coronavirus Variant Spotted in California Raises Alarm

CDC | About the Variants

CDC | SARS-CoV-2 Variant Classifications and Definitions

CDC | Genomic Surveillance for SARS-CoV-2

ABC 13 | New COVID Variant Identified at Texas A&M Lab Suggests Potential Resistance to Antibodies

Houston Chronicle | Texas A&M Researchers Discover a New COVID-19 Variant in College Station

Advisory Board | How Well COVID-19 Vaccines Work Against Variants, According to the Latest Research

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